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Differences between Voacangine and Ibogaine



Voacangine is a drug that has been used medicinally for thousands of years by the Bwiti people in Gabon.

It is derived from the iboga plant, which contains a substance called ibogaine. Ibogaine itself has been used medicinally for centuries and was used by tribes in Africa to treat many health conditions including opiate addiction, depression, and eating disorders.

Voacangine can be smoked, snorted, or swallowed but cannot be injected. Its primary use today is as an alternative treatment for opiate addiction—a process known as detoxification

—but its hallucinatory properties make it an attractive recreational drug too (especially given its low price compared to other hallucinogens).


Table of Contents

1. Chemical synthesis

Differences between Voacangine and Ibogaine

The difference between these two drugs is that one is naturally occurring, while the other is synthesized from a plant alkaloid. 

In the case of ibogaine, it’s found in plants like ayahuasca (an Amazonian plant) or Tabernanthe iboga and Physostigma venenosum (both from Africa). 

Ibogaine has been used for centuries by indigenous tribes for religious purposes and to treat addiction. 

However, there are currently no clinical trials on using it as a treatment for people with opioid use disorder who want to stop using heroin or prescription painkillers.

On the other hand, voacangine has only been studied in animals in laboratories so far—and even then, only under very limited conditions

—but scientists hope to determine whether this drug can be an aid in treating addiction soon enough!


2. Area of use

Ibogaine is used in the treatment of drug addiction. In this context, it can be injected or orally consumed by individuals who are addicted to opioids, alcohol, cocaine, and other substances.

Voacangine is approved by the FDA for use in Parkinson’s disease. 

It’s also used off-label to treat Alzheimer’s disease and epilepsy as well as other neurological disorders that can cause involuntary movements such as Tourette Syndrome (TS).


3. Medical application

While Voacangine and Ibogaine are both used to treat addictions, there are significant differences between them. 

The main difference is that Ibogaine is also used to treat other conditions, such as Alzheimer’s disease and Parkinson’s disease. 

While Voacangine has no medical applications outside of treating addictions, it helps treat cancer patients suffering from chemo-induced nausea or vomiting. 

In addition, Voacangine may help those who smoke cigarettes quit smoking by reducing cravings for nicotine and decreasing withdrawal symptoms like irritability, anxiety, depression, and difficulty sleeping.


4. Effects (hallucinatory and psychedelic)

Both ibogaine and voacangine are hallucinogenic substances.

Ibogaine is a hallucinogen that can induce psychedelic effects similar to LSD, but its primary purpose is to reduce cravings and withdrawal symptoms from drugs such as heroin, cocaine, amphetamines, and methamphetamine.

Voacangine has psychedelic effects similar to LSD as well as hallucinatory properties. 

It’s been used in native rituals for centuries by the natives of Brazil who call it “the dreamer” because of these properties.


5. Limitations on trafficking and cultivation

You can only legally buy ibogaine in a few countries, including Canada and South Africa. 

Importing it into the US is also illegal unless you have a prescription from your doctor. 

The DMT found in voacangine is also illegal to possess, sell or distribute in the US without a license from the DEA.

That said, if you’re purchasing either drug illegally (through an unlicensed seller), there are risks involved

—especially with ibogaine because of its high price tag and potential for abuse. Ibogaine has been shown to be very safe when taken under medical supervision; 

however, voacangine may not be as safe because it hasn’t been studied extensively enough yet to know how much can be safely consumed at one time

—or whether it’s addictive at all.


6. Price (for comparison)

For the sake of comparison, the price of Voacangine is about $1,000 per gram. 

The price for Ibogaine is about $350 per gram (the average dose is about 5-10 grams).

So, if you’re looking for a cheap and legal alternative to ibogaine then it would seem that voacangine might be your best option, but if you want the most effective treatment approach then ibogaine could be right for you!


7. Unique properties compared to other drugs/medicines

  • Voacangine is a legal substance. It is not a controlled substance and does not have any negative effects on your health or well-being.
  • Voacangine is not addictive, unlike other drugs or medicines that have been created by pharmaceutical companies to treat addiction. You cannot build up a tolerance to it either, so you do not need to take more than one dose every time you use the drug (which can be taken in capsule form).
  • Withdrawal symptoms are also unlikely with voacangine because it does not cause physical or psychological dependence on the user, unlike some other medications used for treating withdrawal symptoms like ibogaine or methadone treatment programs.


Summary: Voacangine is gaining popularity as a precursor to Ibogaine, but some people actually prefer Voacangine high

When you look at the chemical structure of Ibogaine, you’ll notice that it’s a derivative of Voacangine. 

If you’ve ever taken Ibogaine, chances are that it was a little bit stronger than what you were used to because Voacangine is more potent than Ibogaine in terms of its psychoactive effects and can produce different side effects.

Some people prefer the experience with Voacangine over taking pure Ibogaine. 

The high from Voacangine lasts longer than the one produced by ibogaine and has been known to be more intense.



Voacangine and Ibogaine are both psychoactive drugs that have been used for hundreds of years in traditional healing ceremonies. 

They have similar effects, but they are different in a few important ways—most notably their legality. 

With careful planning, it’s possible to use these drugs safely and responsibly; however, it is important to understand how each one works so you can make an informed decision about which one might be right for you!


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